Ken Duffy
Professor,
Electrical and Computer Engineering
Professor,
Mathematics
Contact
- k.duffy@northeastern.edu
- 360 Huntington Ave
Boston, MA 02115
Office
- ISEC 409
Lab
- EXP, 6th Floor
Research Focus
Algorithms for communication systems, the life sciences, and DNA forensics. Primary focus currently on new approaches to forward error correction.
About
Ken R. Duffy is a professor at Northeastern University with a joint appointment in the Department of Electrical & Computer Engineering and the Department of Mathematics. He works in works collaborative multi-disciplinary teams to design, analyze, and realize algorithms using tools from probability, statistics, and machine learning. Algorithms he has developed have been implemented in digital circuits and in DNA. His current focus is on modern approaches to error correction coding.
He received a B.A (mod) in Mathematics in 1996 and a PhD in Applied Probability in 2000, both awarded by Trinity College Dublin. He was previously a professor at National University of Ireland, Maynooth, where he was the Director of the Hamilton Institute, an interdisciplinary research centre, from 2016 to 2022. He was one of three co-Directors of the Science Foundation Ireland Centre for Research Training in Foundations of Data Science, which has funded more than 120 PhD students.
He is a co-founder of the Royal Statistical Society’s Applied Probability Section (2011), co-authored a cover article of Trends in Cell Biology (2012), is a winner of a best paper award at the IEEE International Conference on Communications (2015), the best paper award from IEEE Transactions on Network Science and Engineering (2019), the best research demo award from COMSNETS (2022), the best demo award from COMSNETS (2023). He is currently an associate editor of IEEE Transactions on Information Theory and an associate editor of IEEE Transactions on Molecular, Biological, and Multi-Scale Communications.
Education
- PhD, Applied Probability, Trinity College Dublin, 2000
- B.A. (Mod), Mathematics, Trinity College Dublin, 1996
Honors & Awards
- Best student paper award, CISS, 2023.
- Best demo award, COMSNETS, 2023.
- Best research demo award, COMSNETS, 2022.
- Best paper award, IEEE Transactions on Network Science and Engineering, 2019.
- Best Paper Award, IEEE International Conference on Communications (ICC), 2015
- Cover article, Trends in Cell Biology, 2012.
Research Overview
Algorithms for communication systems, the life sciences, and DNA forensics. Primary focus currently on new approaches to forward error correction.
Selected Research Projects
- Development towards a Community Research Platform for sub-THz Satellite Communication Networks
- – Co-Principal Investigator, National Science Foundation
- Interferers in Our Midst
- – Principal Investigator, National Science Foundation
- Guessing Random Additive Noise Decoding, DARPA
Research Centers and Institutes
Department Research Areas
Selected Publications
Information theory, coding, communications:
- K. R. Duffy, M. Grundei & M. Médard. Using channel correlation to improve decoding – ORBGRAND-AI. IEEE Globecom, 2023.
- A. Cohen, R. D’Oliveira, K. Duffy, J. Woo & M. Médard. AES as error correction: cryptosystems for reliable communication. IEEE Communications Letters, 27 (8), 1964–1968, 2023.
- A. Riaz, A. Yasar, F. Ercan, W. An, J. Ngo, K. Galligan, M. Médard, K. R. Duffy & Rabia T. Yazicigil, A sub-0.8 pJ/bit, 16.3 Gbps/mm^2 universal soft-detection decoder using ORBGRAND in 40 nm CMOS. IEEE International Solid-State Circuits Conference, 2023.
- K. R. Duffy, W. An & M. Médard. Ordered reliability bits guessing random additive noise decoding. IEEE Transactions on Signal Processing, 70, 4528–4542, 2022.
- W. An, M. Médard & K. R. Duffy. Keep the bursts and ditch the interleavers. IEEE Transactions on Communications, 70 (6), 3655–3667, 2022.
- K. R. Duffy, M. Médard & W. An. Guessing random additive noise decoding with symbol reliability information (SRGRAND). IEEE Transactions on Communications, 70 (1), 3–18, 2022.
- K. R. Duffy & S. Shneer. MDS coding is better than replication for job completion times. Operations Research Letters, 49 (1), 91–95, 2021.
- H. Wang, L. Vo, F. P. Calmon, M. Médard, K. R. Duffy & M. Varia, Privacy with estimation guarantees, IEEE Transactions on Information Theory, 65 (12), 8025-8042, 2019.
- K. R. Duffy, J. Li & M. Médard, Capacity-achieving guessing random additive noise decoding (GRAND), IEEE Transactions on Information Theory, 65 (7), 4023-4040, 2019.
Life sciences:
- M. B. Horton, H. Cheon, K. R. Duffy, D. Brown, S. H. Naik, C. Alvarado, J. R. Groom, S. Heinzel & P. D. Hodgkin. Lineage tracing reveals B cell antibody class switching is stochastic, cell-autonomous, and tuneable. Immunity, 55 (10), 1843–1855, 2022.
- K. Bresser, L. Kok, A. C. Swain, L. A. King, L. Jacobs, T. S. Weber, L. Perié, K. R. Duffy, R. J. de Boer, F. A. Scheeren & T. N. Schumacher, Replicative history marks functional disparity in the CD8+ T cell memory pool. Nature Immunology, 3(5), 791–801, 2022.
- H. Cheon, A. Kan, G. Prevedello, S. C. Oostinde, S. J. Dovedi, E. D. Hawkins, J. M. Marchingo, S. Heinzel, K. R. Duffy & P. D. Hodgkin. Cyton2: A model of immune cell population dynamics that includes familial instructional inheritance. Frontiers in Bioinformatics, 1, 1–20, 2021.
- T. Tak, G. Prevedello, G. Simon, N. Paillon, C. Benlabiod, C. Marty, J-L. Villeval, I. Plo, K. R. Duffy & L. Perié. HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity. eLife, 10, e60624, 2021.
- M. L. R. Haltalli, S. Watcham, N. K. Wilson, K. Eilers, A. Lipien, H. Ang, F. Birch, S. G. Anton, C. Pirillo, N. Ruivo, M. L. Vainieri, C. Pospori, R. E. Sinden, T. C. Luis, J. Langhorne, K. R. Duffy, B. Göttgens, A. M. Blagborough & C. Lo Celso, Manipulating niche composition limits damage to haematopoietic stem cells during plasmodium infection. Nature Cell Biology, 22, 1399–1410, 2020.
DNA Forensics
- C. M. Grgicak, Q. Bhembe, N. Sheth, K. R. Duffy & D. Lun. Single cell investigative genetics: Single-cell data produces genotype distributions concentrated at the true genotype across all mixture complexities. Forensic Science International: Genetics, to appear.
- K. R. Duffy, D. Lun, M. Mulcahy, L. O’Donnell, N. Sheth & C. M. Grgicak. Evidentiary evaluation of single cells renders highly informative forensic comparisons across multifarious admixtures. Forensic Science International: Genetics, 2023.
- N. Sheth, K. R. Duffy & C. M. Grgicak. High-quality data from a forensically relevant single-cell pipeline enabled by low PBS and Proteinase K concentrations. Journal of Forensic Sciences, 67, 697–706, 2022.
- C. Grgicak, K. R. Duffy, & D. Lun. A posteriori probabilities on the number of contributors when conditioned on a known contributor. Forensic Science International: Genetics, 54, 102563, 2022.
- N. Sheth, H. Swaminathan, A. J. Gonzalez, K. R. Duffy & C. M. Grgicak. Towards developing forensically relevant single cell pipelines by incorporating direct-to-PCR extraction: effects on signal quality and allele dropout. International Journal of Legal Medicine, 135 (3), 727–738, 2021.
- C. M. Grgicak, S. Karkar, X. Yearwood-Garcia, L. E. Alfonse, K. R. Duffy & D. Lun. A large-scale validation of NOCIt’s a posteriori probability of the number of contributors and its integration into forensic interpretation pipelines, Forensic Science International: Genetics, 47, 102296, 2020.
Jan 31, 2025
2024 Stanford University Annual Assessment of Author Citations
The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2% of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above. The list below includes those who published a paper in 2024 or later.

Jan 30, 2025
Faculty and Staff Awards 2025
Faculty and staff were recognized at the 27th Annual College of Engineering Faculty and Staff Awards for their exceptional service and dedication in support of students, the COE community, and the university during the 2024-2025 academic year.

Oct 16, 2024
Developing Worldwide High-Speed Internet Access via Satellite
A group of COE faculty led by ECE Professor and Interim Chair Josep Jornet is partnering with student group Project Horizon and Morehead State University to develop what could be the world’s first sub-THz wireless satellite network testbed.

Aug 19, 2024
Using Interference Structure To Improve Wireless Communication
ECE/COS Professor Ken Duffy, in collaboration with Boston University and MIT, was awarded a $780,000 NSF grant for “Interferers in Our Midst.” The team will develop methods to improve communication performance in shared, congested, and contested spectrum bands.

Jul 08, 2024
Developing the World’s First Sub-THz Satellite Network Platform
ECE Professor and Interim Chair Josep Jornet, MIE Professor Andrew Gouldstone, ECE Professor Kaushik Chowdhury, ECE William Lincoln Smith Professor Tommaso Melodia, and ECE/COS Professor Ken Duffy, in collaboration with the Morehead State University Space Science Center, were awarded a $750,000 NSF grant for the “Development Towards a Community Research Platform for Sub-THz Satellite Communication Networks.”
Dec 07, 2023
2023 Stanford University Annual Assessment of Author Citations
The following COE professors are among the top scientists worldwide selected by Stanford University representing the top 2% of the most-cited scientists with single-year impact in various disciplines. The selection is based on the top 100,000 by c-score (with and without self-citations) or a percentile rank of 2% or above.

Dec 20, 2022
New Faculty Spotlight: Ken Duffy
Ken Duffy joins the Electrical and Computer Engineering department in January 2023 as a Professor with a joint appointment in Mathematics.